Immunogenicity in mice and rhesus monkeys vaccinated with recombinant vaccinia virus expressing bivalent E7E6 fusion proteins from human papillomavirus types 16 and 18

<p>Abstract</p> <p>Background</p> <p>Persistent infection with high-risk human papillomavirus (HPV) is a predominant cause of cervical cancer, and HPV16 and HPV18 occur in 50% and 20% of cervical cancer cases, respectively. The viral oncogenes E6 and E7 are constitutive...

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Bibliographic Details
Main Authors: Tian Houwen, Tan Wenjie, Zhang Hui, Gao Jian, Pang Zheng, Feng Jing, Ren Jiao, Liu Binlei, Zhao Li, Ruan Li
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/8/1/302