Hypoxia-inducible factor-1α in acute ischemic stroke: neuroprotection for better clinical outcome

Background: Hypoxia-inducible factor-1α (HIF-1α) is a transcription factor which maintains cellular homeostasis in response to hypoxia. It can trigger apoptosis while stimulating angiogenesis process and decrease neurological deficit after an ischemic stroke. Up until now, this protein complex has n...

Full description

Bibliographic Details
Main Authors: Lisda Amalia, Henny Anggraini Sadeli, Ida Parwati, Ahmad Rizal, Ramdan Panigoro
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020311300