Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition

<p>Abstract</p> <p>Background</p> <p>Gastric cancer is the second leading cause of cancer mortality in the world. The receptor tyrosine kinase MET is constitutively activated in many gastric cancers and its expression is strictly required for survival of some gastric ca...

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Bibliographic Details
Main Authors: Bertotti Andrea, Migliore Cristina, Sierra J Rafael, Cepero Virna, Ghiso Elena, Corso Simona, Trusolino Livio, Comoglio Paolo M, Giordano Silvia
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/121