Cell-Cycle-Dependent Regulation of Ca2+-Activated K+ Channel in Jurkat T-Lymphocyte

Small-conductance Ca2+-activated K+ (SK2) channel plays an important role in the activation of Jurkat T-lymphocytes by maintaining electrical gradients for the sustained Ca2+ influx. Apamin-sensitive K+ current was significantly decreased with cell-cycle progression from G0/G1 into G2/M phases, and...

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Bibliographic Details
Main Authors: Takashi Morimoto, Susumu Ohya, Hidetoshi Hayashi, Kikuo Onozaki, Yuji Imaizumi
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319342835