CD161 Expression on Mucosa-Associated Invariant T Cells is Reduced in HIV-Infected Subjects Undergoing Antiretroviral Therapy Who Do Not Recover CD4+ T Cells
Background: Mucosa-associated invariant T (MAIT) cells are a recently identified class of innate-like T cells that are involved in the mucosal immune response. MAIT cells are characterized by expression of TCR Va7.2 and CD161. In HIV infection, there is a profound early loss of MAIT cells from the c...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Case Western Reserve University
2017-08-01
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Series: | Pathogens and Immunity |
Subjects: | |
Online Access: | http://paijournal.com/index.php/paijournal/article/view/136 |