Epigenetic reprogramming promotes the antiviral action of IFNα in HBV-infected cells

Abstract Chronic hepatitis B virus (HBV) infections remain a health burden affecting ~250 million people worldwide. Thus far, available interferon-alpha (IFNα)-based therapies have shown unsatisfactory cure rates, and alternative therapeutic molecules are still required. However, their development h...

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Bibliographic Details
Main Authors: Luc Gailhouste, Masayuki Sudoh, Xian-Yang Qin, Koichi Watashi, Takaji Wakita, Takahiro Ochiya, Tomokazu Matsuura, Soichi Kojima, Yutaka Furutani
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00515-y