Rebound of HBV DNA after cessation of nucleos/tide analogues in chronic hepatitis B patients with undetectable covalently closed

Background & Aims: Nucleos(t)ide analogues (NUCs) effectively suppress serum HBV DNA. Previously, we have identified 21 patients with undetectable covalently closed circular DNA (cccDNA) upon long-term NUC therapy. This study investigated the effect of NUC withdrawal in patients with undetec...

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Bibliographic Details
Main Authors: Ching-Lung Lai, Danny Ka-Ho Wong, Gerald Tsz-Yau Wong, Wai-Kay Seto, James Fung, Man-Fung Yuen
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:JHEP Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258955592030046X