Beneficial effect of diosgenin as a stimulator of NGF on the brain with neuronal damage induced by Aβ-42 accumulation and neurotoxicant injection

Beneficial effect of diosgenin as a stimulator of NGF on the brain with neuronal damage induced by Aβ-42 accumulation and neurotoxicant injection

Abstract To investigate the beneficial effects of diosgenin (DC) on the multiple types of brain damage induced by Aβ-42 peptides and neurotoxicants, alterations in the specific aspects of brain functions were measured in trimethyltin (TMT)-injected transgenic 2576 (TG) mice that had been pretreated...

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Bibliographic Details
Main Authors: Eun-Kyoung Koh, Woo-Bin Yun, Ji-Eun Kim, Sung-Hwa Song, Ji-Eun Sung, Hyun-Ah Lee, Eun-Ji Seo, Seung-Wan Jee, Chang-Joon Bae, Dae-Youn Hwang
Format: Article
Language:English
Published: BMC 2016-12-01
Series:Laboratory Animal Research
Subjects:
Diosgenin
neurodegenerative disorder
Aβ-42
trimethyltin
acetylcholinesterase
nerve growth factor
Online Access:http://link.springer.com/article/10.5625/lar.2016.32.2.105

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http://link.springer.com/article/10.5625/lar.2016.32.2.105

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