Estradiol Enhances Anorectic Effect of Apolipoprotein A-IV through ERα-PI3K Pathway in the Nucleus Tractus Solitarius

Estradiol (E2) enhances the anorectic action of apolipoprotein A-IV (apoA-IV), however, the intracellular mechanisms are largely unclear. Here we reported that the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway was significantly activated by E2 and apoA-IV, respectively, in primary neuro...

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Bibliographic Details
Main Authors: Min Liu, Ling Shen, Meifeng Xu, David Q.-H. Wang, Patrick Tso
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/12/1494