Risk Analysis Implications of Dose-Response Thresholds for NLRP3 Inflammasome-Mediated Diseases: Respirable Crystalline Silica and Lung Cancer as an Example
Chronic inflammation mediates an extraordinarily wide range of diseases. Recent progress in understanding intracellular inflammasome assembly, priming, activation, cytokine signaling, and interactions with mitochondrial reactive oxygen species, lysosome disruption, cell death, and prion-like polymer...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2019-04-01
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| Series: | Dose-Response |
| Online Access: | https://doi.org/10.1177/1559325819836900 |