Epitope characterization of an aromatase monoclonal antibody suitable for the assessment of intratumoral aromatase activity.

Immunohistochemistry is one of the most suitable methods for the detection of intratumoral aromatase in order to identify patients who may respond to aromatase inhibitor therapy in hormone-dependent breast cancer. Previous studies showed statistically significant correlation between results of immnu...

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Bibliographic Details
Main Authors: Yanyan Hong, Hongzhi Li, Jingjing Ye, Yasuhiro Miki, Yate-Ching Yuan, Hironobu Sasano, Dean B Evans, Shiuan Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2778552?pdf=render