L-Carnitine Stimulates In Vivo Carbohydrate Metabolism in the Type 1 Diabetic Heart as Demonstrated by Hyperpolarized MRI

L-Carnitine Stimulates In Vivo Carbohydrate Metabolism in the Type 1 Diabetic Heart as Demonstrated by Hyperpolarized MRI

The diabetic heart is energetically and metabolically abnormal, with increased fatty acid oxidation and decreased glucose oxidation. One factor contributing to the metabolic dysfunction in diabetes may be abnormal handling of acetyl and acyl groups by the mitochondria. L-carnitine is responsible for...

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Bibliographic Details
Main Authors: Dragana Savic, Vicky Ball, M. Kate Curtis, Maria da Luz Sousa Fialho, Kerstin N. Timm, David Hauton, James West, Julian Griffin, Lisa C. Heather, Damian J. Tyler
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Metabolites
Subjects:
magnetic resonance
L-carnitine
metabolic imaging
in vivo metabolism
hyperpolarized <sup>13</sup>C
Langendorff perfusion
Online Access:https://www.mdpi.com/2218-1989/11/3/191

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https://www.mdpi.com/2218-1989/11/3/191

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