The Role of Rho GTPases in Toxicity of Clostridium difficile Toxins

Clostridium difficile (C. difficile) is the main cause of antibiotic-associated diarrhea prevailing in hospital settings. In the past decade, the morbidity and mortality of C. difficile infection (CDI) has increased significantly due to the emergence of hypervirulent strains. Toxin A (TcdA) and toxi...

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Bibliographic Details
Main Authors: Shuyi Chen, Chunli Sun, Haiying Wang, Jufang Wang
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/7/12/4874