The BDNF rs6265 Polymorphism is a Modifier of Cardiomyocyte Contractility and Dilated Cardiomyopathy

The BDNF rs6265 Polymorphism is a Modifier of Cardiomyocyte Contractility and Dilated Cardiomyopathy

Brain-derived neurotrophic factor (BDNF) is a neuronal growth and survival factor that harbors cardioprotective qualities that may attenuate dilated cardiomyopathy. In ~30% of the population, BDNF has a common, nonsynonymous single nucleotide polymorphism rs6265 (Val66Met), which might be correlated...

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Bibliographic Details
Main Authors: Frank J. Raucci, Anand Prakash Singh, Jonathan Soslow, Larry W. Markham, Lin Zhong, Wejdan Aljafar, Natasja Lessiohadi, Cassandra P. Awgulewitsch, Prachi Umbarkar, Qinkun Zhang, Presley L. Cannon, Maciej Buchowski, Joseph T. Roland, Erica J. Carrier, William B. Burnette, Antonis K. Hatzopoulos, Hind Lal, Cristi L. Galindo
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
brain-derived neurotrophic growth factor
dilated cardiomyopathy
rs6365 polymorphism
Duchenne muscular dystrophy
Val66Met
Online Access:https://www.mdpi.com/1422-0067/21/20/7466

Internet

https://www.mdpi.com/1422-0067/21/20/7466

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