Potential role for PADI-mediated histone citrullination in preimplantation development

Potential role for PADI-mediated histone citrullination in preimplantation development

<p>Abstract</p> <p>Background</p> <p>The peptidylarginine deiminases (PADIs) convert positively charged arginine residues to neutrally charged citrulline on protein substrates in a process that is known as citrullination or deimination. Previous reports have documented...

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Bibliographic Details
Main Authors: Kan Rui, Jin Mei, Subramanian Venkataraman, Causey Corey P, Thompson Paul R, Coonrod Scott A
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Developmental Biology
Subjects:
Peptidylarginine deiminase
Citrullination
Histone modification
Preimplantation development
Cl-amidine
Online Access:http://www.biomedcentral.com/1471-213X/12/19

Internet

http://www.biomedcentral.com/1471-213X/12/19

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