Estrogen-Dependent Upregulation of Adcyap1r1 Expression in Nucleus Accumbens Is Associated With Genetic Predisposition of Sex-Specific QTL for Alcohol Consumption on Rat Chromosome 4

Estrogen-Dependent Upregulation of Adcyap1r1 Expression in Nucleus Accumbens Is Associated With Genetic Predisposition of Sex-Specific QTL for Alcohol Consumption on Rat Chromosome 4

Humans show sex differences related to alcohol use disorders (AUD). Animal model research has the potential to provide important insight into how sex differences affect alcohol consumption, particularly because female animals frequently drink more than males. In previous work, inbred strains of the...

Full description

Bibliographic Details
Main Authors: John Paul Spence, Jill L. Reiter, Bin Qiu, Hao Gu, Dawn K. Garcia, Lingling Zhang, Tamara Graves, Kent E. Williams, Paula J. Bice, Yi Zou, Zhao Lai, Weidong Yong, Tiebing Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Genetics
Subjects:
alcohol use disorder
sex-difference
congenic rat model
nucleus accumbens
RNA-seq
Adcyap1r1
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00513/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00513/full

Similar Items