Specific trophoblast transcripts transferred by extracellular vesicles affect gene expression in endometrial epithelial cells and may have a role in embryo-maternal crosstalk

Abstract Background Successful establishment of pregnancy hinges on appropriate communication between the embryo and the uterus prior to implantation, but the nature of this communication remains poorly understood. Here, we tested the hypothesis that the endometrium is receptive to embryo-derived si...

Full description

Bibliographic Details
Main Authors: Masoumeh Es-Haghi, Kasun Godakumara, Annika Häling, Freddy Lättekivi, Arina Lavrits, Janeli Viil, Aneta Andronowska, Tamer Nafee, Victoria James, Ülle Jaakma, Andres Salumets, Alireza Fazeli
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Cell Communication and Signaling
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12964-019-0448-x