The relationship between cortical blood flow and sub-cortical white-matter health across the adult age span.

Degeneration of cerebral white matter is commonly observed in aging, and the associated degradation in neural connectivity contributes to cognitive decline in older adults. Vascular dysfunction has been implicated as a potential mechanism for general age-related neural tissue deterioration; however,...

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Bibliographic Details
Main Authors: J Jean Chen, H Diana Rosas, David H Salat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3578934?pdf=render