MITF-independent pro-survival role of BRG1-containing SWI/SNF complex in melanoma cells.

Metastasized malignant melanoma has a poor prognosis because of its intrinsic resistance to chemotherapy and radiotherapy. The central role in the melanoma transcriptional network has the transcription factor MITF (microphthalmia-associated transcription factor). It has been shown recently that the...

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Bibliographic Details
Main Authors: Lubica Ondrušová, Jiri Vachtenheim, Jiri Réda, Petra Záková, Kamila Benková
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3547967?pdf=render