Caspase-1/IL-1β represses membrane transport of GluA1 by inhibiting the interaction between Stargazin and GluA1 in Alzheimer’s disease

Abstract Background Alzheimer's disease is a neurodegenerative disease. Previous study has reported that caspase-1/IL-1β is closely associated with Alzheimer's disease. However, the biological role of caspase-1/IL-1β in Alzheimer's disease has not been fully elucidated. This study aim...

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Bibliographic Details
Main Authors: Xunhu Gu, Hanjun Wu, Yuqin Xie, Lijun Xu, Xu Liu, Wei Wang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-021-00273-8