Effects of Amprenavir on HIV-1 Maturation, Production and Infectivity Following Drug Withdrawal in Chronically-Infected Monocytes/Macrophages

Effects of Amprenavir on HIV-1 Maturation, Production and Infectivity Following Drug Withdrawal in Chronically-Infected Monocytes/Macrophages

A paucity of information is available on the activity of protease inhibitors (PI) in chronically-infected monocyte-derived macrophages (MDM) and on the kinetics of viral-rebound after PI removal in vitro. To fill this gap, the activity of different concentrations of amprenavir (AMP) was evaluated in...

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Bibliographic Details
Main Authors: Ana Borrajo, Alessandro Ranazzi, Michela Pollicita, Rosalinda Bruno, Andrea Modesti, Claudia Alteri, Carlo Federico Perno, Valentina Svicher, Stefano Aquaro
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Viruses
Subjects:
amprenavir
Human immunodeficiency virus
monocytes/macrophages
protease inhibitors
Online Access:https://www.mdpi.com/1999-4915/9/10/277

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https://www.mdpi.com/1999-4915/9/10/277

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