The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons

The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons

Certain neuron types fire spontaneously at high rates, an ability that is crucial for their function in brain circuits. The spontaneously active GABAergic neurons of the substantia nigra pars reticulata (SNr), a major output of the basal ganglia, provide tonic inhibition of downstream brain areas. A...

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Bibliographic Details
Main Authors: Andrew Lutas, Carolina Lahmann, Magali Soumillon, Gary Yellen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-05-01
Series:eLife
Subjects:
spontaneous firing
basal ganglia
leak current
metabolism and excitability
Online Access:https://elifesciences.org/articles/15271

Internet

https://elifesciences.org/articles/15271

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