Exploiting the Chalcone Scaffold to Develop Multifunctional Agents for Alzheimer’s Disease

Exploiting the Chalcone Scaffold to Develop Multifunctional Agents for Alzheimer’s Disease

Alzheimer’s disease still represents an untreated multifaceted pathology, and drugs able to stop or reverse its progression are urgently needed. In this paper, a series of naturally inspired chalcone-based derivatives was designed as structural simplification of our previously reported ben...

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Bibliographic Details
Main Authors: Angela Rampa, Manuela Bartolini, Letizia Pruccoli, Marina Naldi, Isabel Iriepa, Ignacio Moraleda, Federica Belluti, Silvia Gobbi, Andrea Tarozzi, Alessandra Bisi
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Molecules
Subjects:
Alzheimer’s disease
chalcones
cholinesterase inhibitors
antioxidants
neuroprotection
Online Access:http://www.mdpi.com/1420-3049/23/8/1902

Internet

http://www.mdpi.com/1420-3049/23/8/1902

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