Models for Natural Killer Cell Repertoire Formation
Natural killer (NK) cells lyse only cells that do not express sufficient levels of self class I MHC molecules. Inhibition of lysis is mediated by inhibitory receptors expressed by NK cells, such as the murine Ly49 receptors, that bind to MHC class I molecules. Since inhibitory receptor genes and MHC...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2003-01-01
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Series: | Clinical and Developmental Immunology |
Online Access: | http://dx.doi.org/10.1080/10446670310001642140 |