Models for Natural Killer Cell Repertoire Formation

Natural killer (NK) cells lyse only cells that do not express sufficient levels of self class I MHC molecules. Inhibition of lysis is mediated by inhibitory receptors expressed by NK cells, such as the murine Ly49 receptors, that bind to MHC class I molecules. Since inhibitory receptor genes and MHC...

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Bibliographic Details
Main Authors: Mali Salmon-Divon, Petter Höglund, Ramit Mehr
Format: Article
Language:English
Published: Hindawi Limited 2003-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1080/10446670310001642140