Kappa opioid receptors in the central amygdala modulate spinal nociceptive processing through an action on amygdala CRF neurons

Kappa opioid receptors in the central amygdala modulate spinal nociceptive processing through an action on amygdala CRF neurons

Abstract The amygdala plays an important role in the emotional-affective aspects of behaviors and pain, but can also modulate sensory aspect of pain (“nociception”), likely through coupling to descending modulatory systems. Here we explored the functional coupling of the amygdala to spinal nocicepti...

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Bibliographic Details
Main Authors: Guangchen Ji, Volker Neugebauer
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Molecular Brain
Subjects:
Amygdala
Kappa opioid receptor
Spinal dorsal horn
Nociception
Optogenetics
Online Access:http://link.springer.com/article/10.1186/s13041-020-00669-3

Internet

http://link.springer.com/article/10.1186/s13041-020-00669-3

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