The Role of Pyruvate Dehydrogenase Kinase in Diabetes and Obesity

The pyruvate dehydrogenase complex (PDC) is an emerging target for the treatment of metabolic syndrome. To maintain a steady-state concentration of adenosine triphosphate during the feed-fast cycle, cells require efficient utilization of fatty acid and glucose, which is controlled by the PDC. The PD...

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Bibliographic Details
Main Author: In-Kyu Lee
Format: Article
Language:English
Published: Korean Diabetes Association 2014-06-01
Series:Diabetes & Metabolism Journal
Subjects:
Online Access:http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-38-181.pdf