Prognostic Value of a BCSC-associated MicroRNA Signature in Hormone Receptor-Positive HER2-Negative Breast Cancer

Prognostic Value of a BCSC-associated MicroRNA Signature in Hormone Receptor-Positive HER2-Negative Breast Cancer

Purpose: Breast cancer patients with high proportion of cancer stem cells (BCSCs) have unfavorable clinical outcomes. MicroRNAs (miRNAs) regulate key features of BCSCs. We hypothesized that a biology-driven model based on BCSC-associated miRNAs could predict prognosis for the most common subtype, ho...

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Bibliographic Details
Main Authors: Chang Gong, Weige Tan, Kai Chen, Na You, Shan Zhu, Gehao Liang, Xinhua Xie, Qian Li, Yunjie Zeng, Nengtai Ouyang, Zhihua Li, Musheng Zeng, ShiMei Zhuang, Wan-Yee Lau, Qiang Liu, Dong Yin, Xueqin Wang, Fengxi Su, Erwei Song
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:EBioMedicine
Subjects:
Breast cancer stem cell
miRNA
Biology-driven approach
Classifier
Prognosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416303656

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http://www.sciencedirect.com/science/article/pii/S2352396416303656

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