SV40 Assembly In Vivo and In Vitro
The Simian virus 40 (SV40) capsid is a T = 7d icosahedral lattice ∼45 nm in diameter surrounding the ∼5 kb circular minichromosome. The outer shell is composed of 360 monomers of the major capsid protein VP1, tightly bound in 72 pentamers. VP1 is a jellyroll β-barrel, with extending N- and C-termina...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2008-01-01
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Series: | Computational and Mathematical Methods in Medicine |
Online Access: | http://dx.doi.org/10.1080/17486700802168312 |