RNAi-mediated knockdown of pituitary tumor- transforming gene-1 (PTTG1) suppresses the proliferation and invasive potential of PC3 human prostate cancer cells

RNAi-mediated knockdown of pituitary tumor- transforming gene-1 (PTTG1) suppresses the proliferation and invasive potential of PC3 human prostate cancer cells

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Pituitary tumor-transforming gene-1 (PTTG1) is a proto-oncogene that promotes tumorigenesis and metastasis in numerous cell types and is overexpressed in a variety of human tumors. We have demonstrated that PTTG1 expression was up-regulated in both human prostate cancer specimens and prostate cancer...

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Bibliographic Details
Main Authors: S.Q. Huang, Q.J. Liao, X.W. Wang, D.Q. Xin, S.X. Chen, Q.J. Wu, G. Ye
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
PTTG1
Prostate cancer
Cell proliferation
Transwell invasion assay
Anticancer drug resistance
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001100001&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001100001&lng=en&tlng=en

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