SERCA Activity Controls the Systolic Calcium Increase in the Nucleus of Cardiac Myocytes

In cardiomyocytes, nuclear calcium is involved in regulation of transcription and, thus, remodeling. The cellular mechanisms regulating nuclear calcium, however, remain elusive. Therefore, the aim of this study was to identify and characterize the factors that regulate nuclear calcium in cardiomyocy...

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Bibliographic Details
Main Authors: Tobias-Oliver Kiess, Jens Kockskämper
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00056/full