Peroxiredoxin 6 Down-Regulation Induces Metabolic Remodeling and Cell Cycle Arrest in HepG2 Cells

Peroxiredoxin 6 Down-Regulation Induces Metabolic Remodeling and Cell Cycle Arrest in HepG2 Cells

Peroxiredoxin 6 (Prdx6) is the only member of 1-Cys subfamily of peroxiredoxins in human cells. It is the only Prdx acting on phospholipid hydroperoxides possessing two additional sites with phospholipase A2 (PLA2) and lysophosphatidylcholine-acyl transferase (LPCAT) activities. There are contrastin...

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Bibliographic Details
Main Authors: María José López Grueso, Rosa María Tarradas Valero, Hidalgo B. Carmona, Dniel José Lagal Ruiz, José Peinado, Brian McDonagh, Raquel Requejo Aguilar, José Antonio Bárcena Ruiz, Carmen Alicia Padilla Peña
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Antioxidants
Subjects:
peroxiredoxin
thiol redox regulation
redox proteome
redox homeostasis
lipid metabolism
cell cycle
Online Access:https://www.mdpi.com/2076-3921/8/11/505

Internet

https://www.mdpi.com/2076-3921/8/11/505

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