Imatinib resistance was reversed by nilotinib in the acute transformation of chronic myeloid leukemia: A case report

Abstract Chronic myeloid leukemia (CML) is a clonal malignant hematopoietic disorder that arises in a hematopoietic stem cell. Its characteristic cytogenetic abnormality is an abnormal chromosome 22 called the Philadelphia (Ph) chromosome. The BCR‐ABL1 fusion gene in this chromosome can encode a tyr...

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Bibliographic Details
Main Authors: Meng Xiao, Hongjing Zhou, Shuguo Li, Chunlei Xin, Tongfeng Zhao, Yunliang Hao, Shumei Li, Yanyan Liang
Format: Article
Language:English
Published: Wiley 2017-12-01
Series:Precision Radiation Oncology
Subjects:
Online Access:https://doi.org/10.1002/pro6.31