Structure and function of capsid protein in flavivirus infection and its applications in the development of vaccines and therapeutics

Structure and function of capsid protein in flavivirus infection and its applications in the development of vaccines and therapeutics

Abstract Flaviviruses are enveloped single positive-stranded RNA viruses. The capsid (C), a structural protein of flavivirus, is dimeric and alpha-helical, with several special structural and functional features. The functions of the C protein go far beyond a structural role in virions. It is not on...

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Bibliographic Details
Main Authors: Xingcui Zhang, Yanting Zhang, Renyong Jia, Mingshu Wang, Zhongqiong Yin, Anchun Cheng
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Veterinary Research
Subjects:
Flavivirus
capsid protein
ecapsidation
vaccine
therapeutic
Online Access:https://doi.org/10.1186/s13567-021-00966-2

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