Structure and function of capsid protein in flavivirus infection and its applications in the development of vaccines and therapeutics

Abstract Flaviviruses are enveloped single positive-stranded RNA viruses. The capsid (C), a structural protein of flavivirus, is dimeric and alpha-helical, with several special structural and functional features. The functions of the C protein go far beyond a structural role in virions. It is not on...

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Bibliographic Details
Main Authors: Xingcui Zhang, Yanting Zhang, Renyong Jia, Mingshu Wang, Zhongqiong Yin, Anchun Cheng
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Veterinary Research
Subjects:
Online Access:https://doi.org/10.1186/s13567-021-00966-2