Endotoxin-activated microglia injure brain derived endothelial cells via NF-κB, JAK-STAT and JNK stress kinase pathways

<p>Abstract</p> <p>Background</p> <p>We previously showed that microglia damage blood brain barrier (BBB) components following ischemic brain insults, but the underlying mechanism(s) is/are not well known. Recent work has established the contribution of toll-like recept...

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Bibliographic Details
Main Authors: Yenari Midori A, Giffard Rona G, Kacimi Rachid
Format: Article
Language:English
Published: BMC 2011-03-01
Series:Journal of Inflammation
Online Access:http://www.journal-inflammation.com/content/8/1/7