Rab27B-Mediated Metabolic Reprogramming Induces Secretome Acidification and Chemoresistance in Breast Cancer Cells

Rab27B-Mediated Metabolic Reprogramming Induces Secretome Acidification and Chemoresistance in Breast Cancer Cells

The secretory Rab27B small GTPase promotes invasive growth, tumourigenicity and metastasis in oestrogen receptor (ER)-positive human breast cancer cells. Coherently, increased Rab27B expression in breast cancer patients is associated with a poor prognosis. In the present study, bio-energetic profili...

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Bibliographic Details
Main Authors:	An Hendrix, Carla Ciccone, Christian Gespach, Marc Bracke, Olivier De Wever, Wendy Westbroek
Format:	Article
Language:	English
Published:	AboutScience Srl 2013-01-01
Series:	Journal of Circulating Biomarkers
Online Access:	https://doi.org/10.5772/56521

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