Rab27B-Mediated Metabolic Reprogramming Induces Secretome Acidification and Chemoresistance in Breast Cancer Cells
The secretory Rab27B small GTPase promotes invasive growth, tumourigenicity and metastasis in oestrogen receptor (ER)-positive human breast cancer cells. Coherently, increased Rab27B expression in breast cancer patients is associated with a poor prognosis. In the present study, bio-energetic profili...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AboutScience Srl
2013-01-01
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| Series: | Journal of Circulating Biomarkers |
| Online Access: | https://doi.org/10.5772/56521 |