Molecular weight determination of a newly synthesized guanidinylated disulfide-containing poly(amido amine) by gel permeation chromatography

A cationic gene delivery vector, guanidinylated disulfide-containing poly(amido amine) (CAR-CBA), was synthesized by Michael addition reaction between N,N′-cystaminebisacrylamide (CBA) and guanidine hydrochloride (CAR). Gel permeation chromatography (GPC) was used to evaluate the molecular weight of...

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Bibliographic Details
Main Authors: Haonan Xing, Mei Lu, Lei Xian, Jinmin Zhang, Tianzhi Yang, Li Yang, Pingtian Ding
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087616302082