Evidence for the concerted evolution between short linear protein motifs and their flanking regions.

BACKGROUND: Linear motifs are short modules of protein sequences that play a crucial role in mediating and regulating many protein-protein interactions. The function of linear motifs strongly depends on the context, e.g. functional instances mainly occur inside flexible regions that are accessible f...

Full description

Bibliographic Details
Main Authors: Claudia Chica, Francesca Diella, Toby J Gibson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2702822?pdf=render