Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis

Summary: The mechanistic/mammalian target of rapamycin complex 1 (mTORC1) regulates cellular function in various cell types. Although the role of mTORC1 in skeletogenesis has been investigated previously, here we show a critical role of mTORC1/4E-BPs/SOX9 axis in regulating skeletogenesis through it...

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Bibliographic Details
Main Authors:	Takashi Iezaki, Tetsuhiro Horie, Kazuya Fukasawa, Makoto Kitabatake, Yuka Nakamura, Gyujin Park, Yuki Onishi, Kakeru Ozaki, Takashi Kanayama, Manami Hiraiwa, Yuka Kitaguchi, Katsuyuki Kaneda, Takayuki Manabe, Yasuhito Ishigaki, Mutsuhito Ohno, Eiichi Hinoi
Format:	Article
Language:	English
Published:	Elsevier 2018-07-01
Series:	Stem Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213671118302637

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http://www.sciencedirect.com/science/article/pii/S2213671118302637

Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis

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