Systemic Inflammation and Tumour-Infiltrating T-Cell Receptor Repertoire Diversity Are Predictive of Clinical Outcome in High-Grade B-Cell Lymphoma with <i>MYC</i> and <i>BCL2</i> and/or <i>BCL6</i> Rearrangements

Systemic Inflammation and Tumour-Infiltrating T-Cell Receptor Repertoire Diversity Are Predictive of Clinical Outcome in High-Grade B-Cell Lymphoma with <i>MYC</i> and <i>BCL2</i> and/or <i>BCL6</i> Rearrangements

High-grade B-cell lymphoma, with <i>MYC</i> and <i>BCL2</i> and/or <i>BCL6</i> rearrangements (double/triple-hit high grade B-cell lymphoma, HGBL-DH/TH) constitutes a provisional entity among B-cell malignancies with an aggressive behavior and dire prognosis. Whil...

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Bibliographic Details
Main Authors: Vito Olschewski, Hanno M. Witte, Veronica Bernard, Konrad Steinestel, Wolfgang Peter, Hartmut Merz, Johannes Rieken, Harald Biersack, Nikolas von Bubnoff, Alfred C. Feller, Niklas Gebauer
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
immune responses to cancer
lymphoma
antibody immunotherapy
Online Access:https://www.mdpi.com/2072-6694/13/4/887

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https://www.mdpi.com/2072-6694/13/4/887

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