Stimulation of Platelet Death by Vancomycin

Stimulation of Platelet Death by Vancomycin

Background/Aims: Side effects of vancomycin, a widely used antibiotic, include thrombocytopenia. The vancomycin-induced thrombocytopenia has been attributed to immune reactions. At least in theory, thrombocytopenia could result in part from the triggering of apoptosis, which results in cell shrinkag...

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Bibliographic Details
Main Authors: Syeda T. Towhid, Eva-Maria Schmidt, Alexander Tolios, Patrick Münzer, Evi Schmid, Oliver Borst, Meinrad Gawaz, Evi Stegmann, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Platelets
Phosphatidylserine
Caspase-3
Apoptosis
Cell membrane scrambling
Mitochondrial potential
Ca2+
Online Access:http://www.karger.com/Article/FullText/343353

Internet

http://www.karger.com/Article/FullText/343353

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