Platelet P2Y12 is involved in murine pulmonary metastasis.

The involvement of platelets in tumor progression is well recognized. The depletion of circulating platelets or pharmacologic inhibitors of platelet activation decreases the metastatic potential of circulating tumor cells in metastasis mouse models. The platelet ADP receptor P2Y12 amplifies the init...

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Bibliographic Details
Main Authors: Yanhua Wang, Yueping Sun, Ding Li, Lin Zhang, Kemin Wang, Yong Zuo, T Kent Gartner, Junling Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3827483?pdf=render