Protein stability regulators screening assay (Pro-SRSA): protein degradation meets the CRISPR–Cas9 library

Abstract The regulation of protein stability is a fundamental issue for biophysical processes, but there has not previously been a convenient and unbiased method of identifying regulators of protein stability. However, as reported in the article entitled “A genome-scale CRISPR–Cas9 screening method...

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Bibliographic Details
Main Authors: Yuanzhong Wu, Tiebang Kang
Format: Article
Language:English
Published: BMC 2016-06-01
Series:Chinese Journal of Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40880-016-0125-z