Peptidylprolyl Isomerases as In Vivo Carriers for Drugs That Target Various Intracellular Entities
Analyses of sequences and structures of the cyclosporine A (CsA)-binding proteins (cyclophilins) and the immunosuppressive macrolide FK506-binding proteins (FKBPs) have revealed that they exhibit peculiar spatial distributions of charges, their overall hydrophobicity indexes vary within a considerab...
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Format: | Article |
Language: | English |
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MDPI AG
2017-09-01
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Series: | Biomolecules |
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Online Access: | https://www.mdpi.com/2218-273X/7/4/72 |