Peptidylprolyl Isomerases as In Vivo Carriers for Drugs That Target Various Intracellular Entities

Analyses of sequences and structures of the cyclosporine A (CsA)-binding proteins (cyclophilins) and the immunosuppressive macrolide FK506-binding proteins (FKBPs) have revealed that they exhibit peculiar spatial distributions of charges, their overall hydrophobicity indexes vary within a considerab...

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Bibliographic Details
Main Author: Andrzej Galat
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/7/4/72