Fabrication of Adipose-Derived Stem Cell-Based Self-Assembled Scaffold under Hypoxia and Mechanical Stimulation for Urethral Tissue Engineering

Fabrication of Adipose-Derived Stem Cell-Based Self-Assembled Scaffold under Hypoxia and Mechanical Stimulation for Urethral Tissue Engineering

Long urethral strictures are often treated with autologous genital skin and buccal mucosa grafts; however, risk of hair ingrowth and donor site morbidity, restrict their application. To overcome this, we introduced a tissue-engineered human urethra comprising adipose-derived stem cell (ASC)-based se...

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Bibliographic Details
Main Authors: Zahra Rashidbenam, Mohd Hafidzul Jasman, Guan Hee Tan, Eng Hong Goh, Xeng Inn Fam, Christopher Chee Kong Ho, Zulkifli Md Zainuddin, Reynu Rajan, Rizal Abdul Rani, Fatimah Mohd Nor, Mohamad Aznan Shuhaili, Nik Ritza Kosai, Farrah Hani Imran, Min Hwei Ng
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
adipose-derived stem cell
self-assembled scaffold
extracellular matrix
hypoxic condition
tissue engineering
autologous urethral graft
Online Access:https://www.mdpi.com/1422-0067/22/7/3350

Internet

https://www.mdpi.com/1422-0067/22/7/3350

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