Alterations in Rat Accumbens Endocannabinoid and GABA Content during Fentanyl Treatment: The Role of Ghrelin

Alterations in Rat Accumbens Endocannabinoid and GABA Content during Fentanyl Treatment: The Role of Ghrelin

The opioid-induced rise of extracellular dopamine, endocannabinoid anandamide and γ-aminobutyric acid (GABA) concentrations triggered by opioids in the nucleus accumbens shell (NACSh) most likely participate in opioid reward. We have previously demonstrated that systemic administration of ghrelin an...

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Bibliographic Details
Main Authors: Magdalena Sustkova-Fiserova, Chrysostomos Charalambous, Tereza Havlickova, Marek Lapka, Pavel Jerabek, Nina Puskina, Kamila Syslova
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:International Journal of Molecular Sciences
Subjects:
fentanyl
ghrelin
endocannabinoids
anandamide
2-arachidonoylglycerol
GABA
neural reward system
nucleus accumbens shell
ventral tegmental area
microdialysis
Online Access:https://www.mdpi.com/1422-0067/18/11/2486

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https://www.mdpi.com/1422-0067/18/11/2486

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