Nonessential Role for the NLRP1 Inflammasome Complex in a Murine Model of Traumatic Brain Injury

Traumatic brain injury (TBI) elicits the immediate production of proinflammatory cytokines which participate in regulating the immune response. While the mechanisms of adaptive immunity in secondary injury are well characterized, the role of the innate response is unclear. Recently, the NLR inflamma...

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Bibliographic Details
Main Authors: Thomas Brickler, Kisha Gresham, Armand Meza, Sheryl Coutermarsh-Ott, Tere M. Williams, Daniel E. Rothschild, Irving C. Allen, Michelle H. Theus
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2016/6373506