Genetic and environmental factors affecting TNF-α responses in relation to Sudden Infant Death Syndrome

Genetic and environmental factors affecting TNF-α responses in relation to Sudden Infant Death Syndrome

Dysregulation of inflammatory responses has been suggested to contribute to the events leading to sudden infant deaths.Tumour necrosis factor-α (TNF-α) is a key cytokine in inflammatory responses to infection, and one of its single nucleotide polymorphisms, TNF G-308A, was associated with severe re...

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Bibliographic Details
Main Authors: Sophia eMoscovis, Ann eGordon, Osama eAlmadani, Maree eGleeson, Rodney eScott, Sharron eHall, Christine eBurns, Caroline eBlackwell
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Immunology
Subjects:
Infection
cigarette smoke
ethnicity
sudden infant death syndrome
TNF-α
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00374/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00374/full

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