Leptin facilitates the differentiation of Th17 cells from MRL/Mp-Fas lpr lupus mice by activating NLRP3 inflammasome

Leptin facilitates the differentiation of Th17 cells from MRL/Mp-Fas lpr lupus mice by activating NLRP3 inflammasome

Both NLRP3 inflammasome and Th17 cells play important roles in the pathogenesis of systemic lupus erythematosus (SLE). Here we tried to investigate whether leptin promotes the differentiation of Th17 cells from lupus mice by activating the NLRP3 inflammasome. Th17 cells induced from MRL/Mp-Fas lpr m...

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Bibliographic Details
Main Authors: Yiyun Yu, Sisi Fu, Xianglin Zhang, Lingbiao Wang, Li Zhao, Weiguo Wan, Yu Xue, Ling Lv
Format: Article
Language:English
Published: SAGE Publishing 2020-05-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/1753425919886643

Internet

https://doi.org/10.1177/1753425919886643

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